Personal Information You Choose to Provide.When you visit our website you may provide us with two types of information: personal information you knowingly choose to disclose that is collected on an individual basis and website use information collected on an aggregate basis as you and others browse our website. Unfortunately, more studies would need to be done before a definite conclusion could be made. Sometimes, a new mutation is found and it is not yet clear whether the change will cause hearing loss or not. These changes are often called “polymorphisms”. Some changes in these genes are not considered to affect the function of the gene. Mutations were detected but their significance is unknown: The mutation that was found may be unrelated to the hearing loss.Unfortunately, these sequences are rarely analyzed unless a specific mutation is already known. Even though examining the whole coding sequence of the gene will detect most mutations, there are other regions of the gene sequence and surrounding DNA that could contain a mutation. It is possible that the test did not detect the second mutation.If only one mutation is detected, interpretation can be difficult. If two identical mutations or two different mutations in the same gene are found, and these mutations have been previously found to cause Usher syndrome, it can be assumed that the hearing loss is caused by these mutations. Not all genes for Usher syndrome have been identified. However, the patient may have Usher syndrome due to mutations in another gene that causes Usher syndrome. If no mutations are found, and the entire coding sequence was analyzed in a gene, it is unlikely that the hearing loss is caused by mutations in that specific gene. There are four possible outcomes to an Usher gene test:
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